Scientists have discovered that an enzyme ingested as a tablet could palliate the event of eating gluten for those that are intolerant .
The research was pack out by scientist from the School of Medical Sciences at University of Örebro , Sweden . They investigated the effect an enzyme called aspergillus Niger River - derived prolyl endoprotease ( AN - PEP ) has on gluten . The enquiry was presented as part ofDigestive Disease Weekin Chicago , the world ’s largest meeting of gastrointestinal experts .
old studies have demonstrate that AN - PEP can ruin gluten down but only when take in liquid material body via a feeding tube . This study is the first to show the same effect with a normal meal .
In the subject area , 18 gluten - sensitive patients were render either a high dose of AN - PEP , a low pane , or a placebo . They then ate porridge that comprise crumbled wheat berry cookies with gluten in .
The results get that the gluten was broken down by up to about 85 per centum in both the high and low dose group before it reach the small gut , or duodenum . This is where symptoms like feel bloated or queasy often become plain .
" This substance let gluten - sensitive patients to sense safer , for example , when they are out with friend at a restaurant and ca n’t be sure whether something is 100 percent gluten - free , " said Dr Julia König , the subject ’s lead author , in astatement .
" Since even pocket-sized sum of gluten can move gluten - sore patient , this accessory can play an important persona in addressing the residual gluten that is often the causal agency of uncomfortable symptom . "
The survey authors emphasise that this tab is only suited for people who are sensitive to gluten , and not those with celiac disease where the symptoms are much more severe .
It should also be noted that the sample distribution sizing of the study was reasonably small , with more inquiry likely being needed . And the amount of gluten ingested was also down in the mouth , meaning gluten - sensitive people should n’t be anticipating eating gluten - laden meal any time soon .
“ We are not suggesting that AN - PEP will give these individuals the ability to eat on pizza pie or alimentary paste , sources of large amount of gluten , but it might make them feel proficient if they erroneously consume gluten , ” said König .
